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Clinical application of the first case of 3D printing in China to degrade the tracheal stent

Case introduction

Ms. Wu, 46 years old, more than half of the trachea soften, collapse, tracheal the narrowest part of only 3 mm, leaving only a seam, under such a situation, the patient is no getter methods, also in lung secretions and sputum no way discharged to breathe is seriously hindered and endanger life. In order to save the patient, Xi'an Jiaotong University machinery manufacturing and system engineering, State Key Laboratory of Professor, "a guide in 3D" senior expert Li Dichen professor and Professor Jian Kang he combined Tangdu Hospital thoracic surgery challenges the extreme difficulty, degradable materials equipment and technology by using the latest 3D printing, clear the airway of patients, to ensure the patients to normal breathing. The surgery was completed in March 28, 2016, set a record in China, becoming the first case of 3D printing biodegradable polymer materials used in clinical medicine.

Background and methods

The general human tracheal about 12 cm long and patients for up to 6 cm of the trachea has softened collapse, blocking the airway is very narrow, only 3 mm, so the disease in clinical practice is very rare and blocking section exceeds the limiting length of resection of the trachea, so can not be removed. As in accordance with the traditional program, the stent implantation, it will cause problems such as sputum discharge.

Based on the patient's CT imaging data, preoperative preparation of the 3D print trachea model, Li Xiaofei, director and Professor Cao Tiesheng fully assess the condition after the decision to implement the suspension. In director Li repeatedly research, "a guide 3D" Jian Kang he professor decided to adopt poly caprolactone absorbable biomaterial, and specialized in building special 3D printing platform, the stent was prepared within 2-3 years gradually degraded and was absorbed into the body, eliminating the second surgery for patients take support the pain. The degradation cycle of the tracheal stent is adjustable, and the control method is a kind of control method for controlling the type and molecular weight of the biological material. The poly - has good biological compatibility, so that it can effectively solve the problem of tracheal stenosis, but also to avoid the adverse reaction after stent implantation.

result

3D printing of the trachea suspension bracket structure design reasonable, excellent mechanical properties, operation after the collapse of the trachea is external stent lifted and suture fixation, to clear the airway, ensure that the patient can breathe normally. Preoperative pulmonary secretions and sputum can't row out, resulting in patients with bilateral severe obstructive pneumonia, postoperative obstructive pneumonia of the left has automatically been healed.

discuss

Tracheal surgery is the Department of thoracic surgery "crown jewel", it once a problem is difficult to solve, because he is limited in length, to provide a more limited part of the doctor removed. Therefore, the use of 3D printing new technology to solve this part of the problem, not only the progress of tracheal surgery, it is a great progress of human.

According to Li Xiaofei, director of introduction, long segment tracheal resection and need will sew the patient's jaw in the chest for a period of time, because of the excessive stretch induced tracheal suture is disengaged, so postoperative patients with painful; endotracheal stent placement will cause difficulties expectoration prevention issues.

Use 3D printing tracheal stents is absorbable biomaterial, has good biological compatibility, so as to effectively solve the problem of tracheal stenosis, and can avoid stent implantation after adverse reactions, the maximum reduce the pain of patients. The surgery to refresh the record, becoming the first case of 3D printing biodegradable polymer materials for clinical medicine successful example, is the future of the effective treatment of tracheal sclerosis.

(left two: Professor He Jiankang, left five: Li Xiaofei, director, left six: Professor Cao Tiesheng

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